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Bio-Age Activate References
AMPK Charge + https://www.quicksilverscientific.com/ampkchargereferences/
[1] Herzig S and Shaw RJ. AMPK: guardian of metabolism and mitochondrial homeostasis. Nat Rev Mol Cell Biol. 2018; 19(2): 121-135.
[2] Hardie DG, et al. Targeting an energy sensor to treat diabetes. Science. 2017; 357 (6350): 455-456.
[3] Foretz M and Viollet B. Activation of AMPK for a break in hepatic lipid accumulation and circulating cholesterol. EBio Medicine. 2018; 31: 15-16.
[4] Tamargo-Gomez I, et al. AMPK: Regulation of metabolic dynamics in the context of autophagy. Int J Mol Sci. 2018; 19(12): 3812.
[5] Furman D, et al. Chronic inflammation in the etiology of disease across the life span. Nature Medicine. 2019; 25: 1822-1832.
[6] Jeon SM, et al. Regulation and function of AMPK in physiology and diseases. Exp Mol Med. 2016; 48: e245.
[7] Shirwany NA and Zou MH. AMPK in cardiovascular health and disease. Acta Pharmacol Sin. 2010; 31(9): 1075-1084.
[8] Ruderman NB, et al. AMPK, insulin resistance, and the metabolic syndrome. J Clin Investig. 2013.
[9] Seabright AP, et al. AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner. FASEB J. 2020; 34(5): 6284-6301.
[10] Ruderman NB, et al. AMPK and SIRT1: a long-standing partnership? Am J Physiol Endocrinol Metab. 2010; 298(4): E751-E760.
[11] Pan H and Finkel T. Key proteins and pathways that regulate lifespan. J Biol Chem. 2017; 292(16): 6452-6460.
[12] Connell NJ, et al. NAD+ metabolism as a target for metabolic health: have we found the silver bullet? Diabetologia. 2019; 62(6): 888-899.
[13] Anton SD, et al. Flipping the metabolic switch: Understanding and applying health benefits of fasting. Obesity (Silver Spring).
[14] Fan W and Evans RM. Exercise mimetics: Impact on health and performance. Cell Metab. 2017; 25(2): 242-247.
[15] Dolinksy VW, et al. Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats. J Physiol. 2012; 590(Pt 11): 2783-2799.
[16] Konrad M and Nieman DC. Evaluation of quercetin as a countermeasure to exercise-induced physiological stress. antioxidants in sports nutrition. 2015.
[17] Kaeberlein M, et al. Substrate-specific activation of sirtuins by resveratrol. J Biol Chem. 2005; 280(17): 17038-17045.
[18] Park D, et al. Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition. Sci Rep. 2016; 6: 21772.
[19] Grant R. Resveratrol increases intracellular NAD+ levels through the up-regulation of the NAD+ synthetic enzyme nicotinamide mononucleotide adenylyltransferase. Nature Precedings. 2010.
[20] Csiszar A, et al. Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol.
[21] Sun H, et al. Berberine ameliorates blockade of autophagic flux in the liver by regulating cholesterol metabolism and inhibiting COX2-prostaglandin synthesis. Cell Death & Dis. 2018; 9: 824.
[22] Lee YS, et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Pharmacol & Ther. 2006; 55(8).
[23] Gomes AP, et al. Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Biochim Biophys Acta. 2012; 1822(2): 185-195.
[24] Rayamajhi N, et al. Quercetin induces mitochondrial biogenesis through activation of HO-1 in HepG2 Cells. Oxid Med Cell Longev. 2013; 2013: 154279.
[25] Li Y, et al. Quercetin, inflammation and immunity. Nutrients. 2016; 8(3): 167.
[26] Kim SG, et al. Quercetin-induced AMP-activated protein kinase activation attenuates vasoconstriction through LKB1-AMPK signaling pathway. J Med Food. 2018; 21(2): 146-153.
[27] Lewinska A, et al. AMPK-mediated senolytic and senostatic activity of quercetin surface functionalized Fe3O4 nanoparticles during oxidant-induced senescence in human fibroblasts. Redox Biol. 2020; 28: 101337.
[28] Van Deursen JM. Senolytic therapies for healthy longevity. Science. 2019; 364(6441): 636-637.
[29] Weng Z, et al. Quercetin Is more effective than Cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. PLoS One. 2012; 7(3): e33805.
[30] Jiang K, et al. Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells. Oncol Rep. 2015; 33(6): 2711-2718.
[31] Lovelace ES, et al. Silymarin suppresses cellular inflammation by inducing reparative stress signaling. J Nat Prod. 2015; 78(8): 1990-2000.
[32] Ye Y, et al. 3,3′-Diindolylmethane induces anti-human gastric cancer cells by the miR-30e-ATG5 modulating autophagy. Biochem Pharmacol. 2016; 115: 77-84.
[33] Hornero RA, et al. The impact of dietary components on regulatory T cells and disease. Front Immunol. 2020; 11: 253.
[34] Shen Y, Honma N et al. Cinnamon extract enhances glucose uptake in 3T3-L1 adipocytes and C2C12 myocytes by inducing LKB1-AMPactivated protein kinase signaling. PLoS One. 2014 Feb 14;9(2):e8789
[35] Park KR, Nam D. β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation. Cancer Lett. 2011 Dec 22;312(2):178-88
[36] Mollazadeh H and Hosseinzadeh H. Cinnamon effects on metabolic syndrome: a review based on its mechanisms. Iran J Basic Med Sci. 2016; 19(12): 1258-1270.
NAD + Platinum https://www.quicksilverscientific.com/nadplatinumreferences/
[1] Longo VD et al. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell 14 (4): 497-510.
[2] Fang EF et al. NAD (+) in aging: molecular mechanisms and translational implications. Trends Mol Med. 2017;23(10):899–916
[3] Keller K and Engelhardt M. Strength and muscle mass loss with the aging process. Age and strength loss. Muscles Ligaments Tendons J. 2013; 3(4): 346-350.
[4] Chang AM and Halter JB. Aging and insulin secretion. Am J Physiol Endocrinol Metab. 2003; 284(1): E7-12.
[5] Caito SW and Aschner M. NAD+ Supplementation attenuates methylmercury dopaminergic and mitochondrial toxicity in Caenorhabditis Elegans. Toxicol Sci. 2016; 151(1): 139-149.
[6] Gizem Kivrak E, et al. Effects of electromagnetic fields exposure on the antioxidant defense system. J Microsc Ultrastruct. 2017; 2017; 5(4): 167-176.
[7] Xie N, et al. NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Signal Transduct Target Ther. 2020; 5: 227.
[8] Hong W, et al. Nicotinamide mononucleotide: A promising molecule for therapy of diverse diseases by targeting NAD+ metabolism. Front Cell Dev Biol. 2020.
[9] Wu, L et al. The elusive NMN transporter is found. Nat Metab 2019: 1; 8-9
[10] Yamaguchi S and Yoshino J. Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy. Bioessays. 2017; 39(5): 10.1002/bies.201600227.
[11] Guarente L, Franklin H. Epstein lecture: sirtuins, aging, and medicine. N Engl J Med. (2011) 364:2235–44.
[12] Kane AE, Sinclair DA. Sirtuins and NAD+ in the development and Treatment of Metabolic and Cardiovascular Diseases. Circ Res. 2018; 123:868-885.
[13] Mangerich A, et al. Pleiotropic cellular functions of PARP1 in longevity and aging: Genome maintenance meets inflammation. Oxid Med Cell Longev. 2012; 2012: 321653.
[14] Bonkowski MS and Sinclair D. Slowing aging by design: the rise of NAD+ and sirtuin-activating compounds. Nat Rev Mol Cell Biol. 2016; 17(11): 679-690.
[15] Lewinska A, et al. AMPK-mediated senolytic and senostatic activity of quercetin surface functionalized Fe3O4 nanoparticles during oxidant-induced senescence in human fibroblasts. Redox Biol. 2020; 28: 101337.
[16] Jesko H, et al. Sirtuins and their roles in brain aging and neurodegenerative disorders. Neurochem Res. 2017; 42(3): 876-890.
[17] Warren JL, et al. Regulation of adaptive immune cells by sirtuins. Front Endocrinol (Lausanne). 2019; 10:466.
[18] Radak Z, et al. The systemic role of SIRT1 in exercise mediated adaptation. Redox Biol. 2020; 35: 101467.
[19] Vargas-Ortiz K, et al. Exercise and sirtuins: A way to mitochondrial health in skeletal muscle. Int J Mol Sci. 2019; 20(11): 2717.
[20] Asher G, et al. SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell. 2008; 134(2): 317-328.
[21] Grabowska W, et al. Sirtuins, a promising target in slowing down the ageing process. Biogerontology. 2017; 18(4): 447-476.
[22] Schafer MJ, et al. Exercise prevents diet-induced cellular senescence in adipose tissue. Diabetes. 2016; 65(6): 1606-1615.
[23] Han YM, et al. β-Hydroxybutyrate prevents vascular senescence through hnRNP A1-mediated upregulation of Oct4.Mol Cell. 2018; 71(6): 1064-1078.
[24] Weng Z, et al. Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. PLoS One. 2012; 7(3): e33805.
[25] Mohar DS and Malik S. The sirtuin system: The holy grail of resveratrol? J Clin Exp Cardiol. 2012; 3(11): 216.
[26] Hustad S, et al. Riboflavin and methylenetetrahydrofolate reductase. Madame Curie Bioscience Database. 2013.
[27] Ahn H, Park JH. Liposomal delivery systems for intestinal lymphatic drug transport.Biomater Res. 2016 Nov 23;20:36 View Full Paper
[28] Alyautdin R et al. Nanoscale drug delivery systems and the blood brain barrier. Int J Nanomedicine. 2014 Feb 7;9:795-811 View Full Paper
Glutathione https://www.quicksilverscientific.com/glutathionereferences/
[1] Homma T et al. Application of glutathione as anti-oxidative and anti-aging drugs. Curr Drug Metab. 2015;16(7):560-71 View Abstract
[2] Ighodaroab OM et al. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid. Alexandria Journal of Medicine 2018 (54): 287-293 View Abstract
[3] Szarka A et al. The ascorbate-glutathione-α-tocopherol triad in abiotic stress response. Int J Mol Sci. 2012;13(4):4458-83View Full Paper
[4] Balendiran GK et al. Cell Biochem Funct. The role of glutathione in cancer. 2004 Nov-Dec;22(6):343-52. View Abstract
[5] Mari M et al. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal. 2009 Nov;11(11):2685-70 View Full Paper
[6] Perricone C et al. Glutathione: a key player in autoimmunity. Autoimmun Rev. 2009 Jul;8(8):697-701. View Abstract
[7] Dröge W et al. Glutathione and immune function. Proc Nutr Soc. 2000 Nov;59(4):595-600. Review. View Abstract
[8] Bajic VP et al. Glutathione “redox homeostasis” and its relation to cardiovascular disease. Oxidative Medicine and Cellular Longevity 2019 View Abstract
[9] Pizzorno J. Glutathione! Integrative Medicine 2014 (13):1:8-12 View Full Paper
[10] Forman HJ. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2009 Feb-Apr;30(1-2):1-12. View Abstract
[11] Hodges RE et al. Modulation of metabolic detoxification pathways using foods and food-derived components: a scientific review with clinical application. J Nutr Metab. 2015;2015:760689 View Full Paper
[12] Keum YS. Regulation of Nrf2-mediated phase II detoxification and anti-oxidant genes. Biomol Ther. 2012;20(2):144-151. View Abstract
[13] Fraternale A et al. Glutathione and glutathione derivatives in immunotherapy. Biol Chem. 2017 Feb 1;398(2):261-275 View Abstract
[14] Kamide Y. Allergy. Intracellular glutathione redox status in human dendritic cells regulates IL-27 production and T-cell polarization. Allergy. 2011 Sep;66(9):1183-92. View Abstract
[15] Dröge W et al. Functions of glutathione and glutathione disulfide in immunology and immunopathology. FASEB J 1994;8:1131–8. View Abstract
[16] Gambhir JK et al. Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis. Clin Biochem 1997;30:351–5. View Abstract
[17] Ortona E, Redox state, cell death and autoimmune diseases: a gender perspective. Autoimmun Rev 2008;7:579–84. View Abstract
[18] Griffiths HR. Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease? Autoimmun Rev 2008;7:544–9. View Abstract
[19] Burek CL, Rose NR. Autoimmune thyroiditis and ROS. Autoimmun Rev 2008;7:530–7. View Abstract
[20] Gheita TA et al. Measurement of malondialdehyde, glutathione, and glutathione peroxidase in SLE patients. Methods Mol Biol. 2014;1134:193-9 View Abstract
[21] Kumar D et al. A link between maternal malnutrition and depletion of glutathione in the developing lens: a possible explanation for idiopathic childhood cataract? Clin Exp Optom. 2013 Nov;96(6):523-8 View Abstract
[22] Teskey G. Glutathione as a marker for human disease. Adv Clin Chem. 2018;87:141-159. View Abstract
[23] Jiang S et al. Glutathione protects against hepatic injury in a murine model of primary Sjögren’s syndrome. Bosn J Basic Med Sci. 2016 Aug 2;16(3):227-31 View Abstract
[24] Sinha R et al. Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function. Eur J Clin Nutr. 2018 Jan;72(1):105-111 View Abstract
[25] Drisko JA. Chelation Therapy. In: Integrative Medicine (Fourth Edition) 2018: (107): 1004-1014.
[26] Lawley SD et al. Mathematical modeling of the effects of glutathione on arsenic methylation. Theor Biol Med Model. 2014 May 16;11:20. View Abstract
[27] Guildford FT et al. Deficient glutathione in the pathophysiology of mycotoxin-related illness. Toxins (Basel). 2014 Feb 10;6(2):608-23 View Full Paper
[28] Hope JH et al. A review of the diagnosis and treatment of ochratoxin a inhalational exposure associated with human illness and kidney disease including focal segmental glomerulosclerosis. J. Environ. Public Health 2012: 2012, 835059. View Abstract
[29] Damy T et al. Glutathione deficiency in cardiac patients is related to the functional status and structural cardiac abnormalities. PLoS One 2009. (4):3: e4781 vol. 4. View Abstract
[30] Biswas SK et al. Depressed glutathione synthesis precedes oxidative stress and atherogenesis in Apo-E−/− Biochemical and Biophysical Research Communications 2005 (338): 3: 1368–1373View Abstract
[31] Shimizu H et al. Relationship between plasma glutathione levels and cardiovascular disease in a defined population: the Hisayama study. Stroke. 2004 (35):9: 2072-2077 View Abstract
[32] de la Asuncion JG et al. Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA. The FASEB Journal. 1996;10(2):333–338. View Abstract
[33] Rae CD et al. Glutathione in the human brain: Review of its roles and measurement by magnetic resonance spectroscopy. Anal Biochem. 2017 Jul 15;529:127-143. View Abstract
[34] Saharan S et al. The emerging role of glutathione in Alzheimer’s disease J Alzheimers Dis. 2014;40(3):519-29. View Abstract
[35] Gambhir JK et al. Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis. Clin Biochem 1997;30:351–5. View Abstract
[36] Ortona E, Redox state, cell death and autoimmune diseases: a gender perspective. Autoimmun Rev 2008;7:579–84. View Abstract
[37] Griffiths HR. Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease? Autoimmun Rev 2008;7:544–9. View Abstract
[38] Burek CL, Rose NR. Autoimmune thyroiditis and ROS. Autoimmun Rev 2008;7:530–7. View Abstract
[39] Gheita TA et al. Measurement of malondialdehyde, glutathione, and glutathione peroxidase in SLE patients. Methods Mol Biol. 2014;1134:193-9 View Abstract
[40] Kumar D et al. A link between maternal malnutrition and depletion of glutathione in the developing lens: a possible explanation for idiopathic childhood cataract? Clin Exp Optom. 2013 Nov;96(6):523-8 View Abstract
[41] Teskey G. Gluathione as a marker for human disease. Adv Clin Chem. 2018;87:141-159. View Abstract
[42] Jiang S et al. Glutathione protects against hepatic injury in a murine model of primary Sjögren’s syndrome. Bosn J Basic Med Sci. 2016 Aug 2;16(3):227-31 View Abstract
Membrane Mend™ https://www.quicksilverscientific.com/membranemendreferences/
[1] Casares D, et al. Membrane lipid composition: Effect on membrane and organelle structure, function and compartmentalization and therapeutic avenues. Int J Mol Sci. 2019; 20(9): 2167.
[2] Leekumjorn S, et al. The role of fatty acid unsaturation in minimizing biophysical changes on the structure and local effects of bilayer membranes. Biochim Biophys Acta. 2009; 1788(7): 1508-1516.
[3] Van Meer G, et al. Membrane lipids: where they are and how they behave. Nat Rev Mol Cell Biol. 2009; 9(2): 112-124.
[4] Zorova LD, et al. Mitochondrial membrane potential. Anal Biochem. 2018; 552: 50-59.
[5] Chew S, et al. Impairment of mitochondrial function by particulate matter: Implications for the brain. Neurochem Int. 2020; 135(104694).
[6] Zulkifli-Cunningham Z, et al. Clinical effects of chemical exposures on mitochondrial function. Toxicology. 2017; 391: 90-99.
[7] Lin JH, et al. Endoplasmic reticulum stress in disease pathogenesis. Annu Rev Pathol. 2008; 3: 399-425.
[8] Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell. 2010; 140(6): P900-P917.
[9] Kalghatgi S, et al. Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells. Sci Transl Med. 2013; 5(192): 192ra85.
[10] Santini SJ, et al. Role of Mitochondria in the Oxidative Stress Induced by Electromagnetic Fields: Focus on Reproductive Systems. Oxid Med Cell Longev. 2018; 2018: 5076271.
[11] Zorova LD, et al. Mitochondrial membrane potential. Anal Biochem. 2018; 552: 50-59.
[12] Nicolson GL, et al. Clinical uses of membrane lipid replacement supplements in restoring membrane function and reducing fatigue in chronic diseases and cancer. Discoveries (Craiova). 2016; 4(1): e54.
[13] Na JY, et al. Hepatoprotective effect of phosphatidylcholine against carbon tetrachloride liver damage in mice. Biochem Biophys Res Commun. 2015; 460(2): 308-313.
[14] Maev IV, et al. Effectiveness of phosphatidylcholine in alleviating steatosis in patients with non-alcoholic fatty liver disease and cardiometabolic comorbidities (MANPOWER study). BMJ Open Gastroenterol. 2020; 7: e000341.
[15] Kennelly JP, et al. Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis. J Lipid Res. 2018; 59(9): 1695-1708.
[16] Schneider H, et al. Lipid-based therapy for ulcerative colitis—Modulation of intestinal mucus membrane phospholipids as a tool to influence inflammation. Int J Mol Sci. 2010; 11(10): 4149-4164.
[17] Chen M, et al. Oral phosphatidylcholine improves intestinal barrier function in drug-induced liver injury in rats. Gastroenterol Res Pract. 2019; Article ID 8723460.
[18] Lichtenberger LM. Role of phospholipids in protection of the GI mucosa. Digestive Dis Sci. 2013; 58: 891-893.
[19] Blusztajn JK, et al. Neuroprotective actions of dietary choline. Nutrients. 2017; 9(8): 815.
[20] Ojo JO, et al. Disruption in brain phospholipid content in a humanized tau transgenic model following repetitive mild traumatic brain injury. Front Neurosci. 2018; [online].
[21] Yu C, et al. HC diet inhibited testosterone synthesis by activating endoplasmic reticulum stress in testicular Leydig cells. J Cell Molec Med. 2019; 23(5): 3140-3150.
[22] Wen G, et al. Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and their key transcriptional regulators in FRTL-5 thyrocytes. PLoS One. 2017; [online].
[23] Lefort N, et al. Dietary Buglossoides Arvensisoil increases circulating n-3 polyunsaturated fatty acids in a dose-dependent manner and enhances lipopolysaccharide-stimulated whole blood interleukin-10—A randomized placebo-controlled trial. Nutrients. 2017; 9(3): 261.
[24] Lefort N, et al. Consumption of Buglossoides arvensis seed oil is safe and increases tissue long-chain n-3 fatty acid content more than flaxseed oil – results of a phase I randomised clinical trial. J Nutr Sci. 2016; 5: e2.
[25] Sztretye M, et al. Astaxanthin: A potential mitochondrial-targeted antioxidant treatment in diseases and with aging. Oxid Med Cell Longev. 2019; 2019: 3849692.
Ultra Binder® Stick Packs Universal Toxin Binder https://www.quicksilverscientific.com/ultrabinderreferences/
[1] Frolis VV, Nikolav VG et al. Effect of enteroabsorption on animal lifespan. Biomat. Art. 1989. 17(3): 341-351.
[2] Su W, Ding X. Methods of endotoxin detection. J Lab Autom. 2015 Aug;20(4):354-64
[3] Aitken AE, Richardson TA et al. Regulation of drug-metabolizing enzymes and transporters in inflammation. Annu Rev Pharmacol Toxicol 2006: 46:123–149
[4] Bolder U, Ton-Nu HT et al. Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion. Gastroenterology 1997: 112:214–225.
[5] Cherrington NJ, Slitt AL et al. Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats. Drug MetabDispos2004: 32:734–741
[6] Tang W, Yi C et al. Endotoxin downregulates hepatic expression of P-glycoprotein and MRP2 in 2-acetylaminofluorene-treated rats. 2000 Mol Cell Biol Res Commun 4:90–97
[7] Maklad A, Emara A et al. Pediatric poisoning in Egypt. Journal of Applied Pharmaceutical Science, 2012 2 (2): 1-6.
[8] Khalid J, Zailaey A. Medical and environmental applications of activated charcoal: review article. European Scientific Journal January 2015 (11): 3: 50-56
[9] Neuvonen J, Olkkola KT. Oral activated charcoal in the treatment of intoxications: role of single and repeated doses. Med Toxicol, 1988: 3; 33-58
[10] Karnib M, Kabbani A et al. Heavy metals removal using activated carbon, silica and silica activated carbon composite. Energy Procedia 2014: 50, 113 – 120.
[11] Du XN, Niu Z et al. Effect of activated charcoal on endotoxin adsorption. Part I. An in vitro study. Biomater Artif Cells Artif Organs. 1987;15(1):229-35
[12] Dalefield R. Emergency care and stabilization of the poisoned patient. In: Veterinary Toxicology for Australia and New Zealand, 2017: 19-32
[13] Rodriguez-Reinoso. Activated carbon and adsorption. in Encyclopedia of Materials: Science and Technology, 2001: 22-24
[14] Krasopoulos JC, De Bari VA et al The adsorption of bile salts on lipids. 1980 May;15(5):365-70
[15] Neuvonen PJ, Kuusisto P. Activated charcoal in the treatment of hypercholesterolaemia: dose-response relationships and comparison with cholestyramine Eur J Clin Pharmacol. 1989;37(3):225-30
[16] Musso CG, Michelangelo H et al. Combination of oral activated charcoal plus low protein diet as a new alternative for handling in the old end-stage renal disease patients Saudi J Kidney Dis Transpl. 2010 Jan;21(1):102-4
[17] Koide, S. S. Chitin-chitosan: properties, benefits and risks. Nutrition Research 1998;8(6):1091-1101
[18] Macchi G. A new approach to the treatment of obesity: chitosan’s effects on body weight reduction and plasma cholesterol levels. Acta Toxicol Ther 1996;17:303-320
[19] Lütjohann D, Marinova M. Nutrients. Influence of Chitosan Treatment on Surrogate Serum Markers of Cholesterol Metabolism in Obese Subjects. 2018 Jan 11;10(1)
[20] Maezaki Y, Tsuji K et al. Hypocholesterolaemic effect of chitosan in adult males. Biosc Biochem Biotech 1993;57:1439-1444
[21] Shoemaker, RC. (2001) Desperation Medicine. Gateway Press: Baltimore. 2. Shoemaker, RC, Schaller J, Schmidt P. (2005) Mold Warriors: Fighting America’s Hidden Threat. Gateway Press: Baltimore
[22] Karunasena E, Larrañaga MD et al. Building-Associated neurological damage modeled in human cells: a mechanism of neurotoxic effects by exposure to mycotoxins in the indoor environment. Mycopathologia. 2010 Dec;170(6):377-90
[23] Carretero MI. Clay minerals and their beneficial effects upon human health. A review. Appl Clay Sci 2002; 21: 155–63.
[24] Herrera P, Burghardt RC et al. Adsorption of Salmonella enteritidis by cetylpyridinium-exchanged montmorillonite clays. Vet Microbiol 2000; 74: 259–72
[25] Haydel SE, Remenih CM. J Broad-spectrum in vitro antibacterial activities of clay minerals against antibiotic-susceptible and antibiotic-resistant bacterial pathogens Antimicrob Chemother. 2008 Feb;61(2):353-61
[26] Schaumberger S, Ladining A et al. Evaluation of the endotoxin binding efficiency of clay minerals using the Limulus Amebocyte lysate test: an in vitro study. MB Express. 2014; 4: 1
[27] Bland, Jeffrey. Effect of orally consumed Aloe vera Juice on Gastrointestinal Function in Normal Humans. Preventative Medicine, March-April 1985
[28] Marzorati M. In vitro modulation of the human gastrointestinal microbial community by plant-derived polysaccharide-rich dietary supplements. Int J Food Microbiol. 2010 May 15;139(3):168-76.
[29] Im SA, Lee YR et al. In vivo evidence of the immunomodulatory activity of orally administered Aloe vera gel. Arch Pharm Res. 2010 Mar;33(3):451-6.
[30] Visuthikosol V, Chowchuen B et al. Effect of aloe vera gel to healing of burn wound a clinical and histologic study. J Med Assoc Thai. 1995 Aug;78(8):403-9
[31] Im SA, Oh ST et al. Identification of optimal molecular size of modified Aloe polysaccharides with maximum immunomodulatory activity. International Immunopharmacology. 2005;5(2):271-279
[32] Hu Y, Xu J, Hu Q. Evaluation of antioxidant potential of aloe vera (Aloe barbadensis miller) extracts. J Agric Food Chem. 2003 Dec 17;51(26):7788-91
[33] Eshun, K., He, Q. Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries—a review. Crit. Rev. Food Sci. Nutr. 2004: 44, 91–96
[34] Mohamed RE, Gadour MO. The lowering effect of Gum Arabic on hyperlipidemia in Sudanese patients. Front Physiol. 2015 May 18;6:160
[35] Crociani F, Alessandrini A et al. Degradation of complex carbohydrates by Bifidobacterium spp. Int.J Food Microbiol. 1994;24:199-210.
[36] Walter DJ, Eastwood MA et al. Fermentation of wheat bran and gum arabic in rats fed on an elemental diet. Br.J.Nutr. 1988;60:225-32
[37] Wyatt GM, Bayliss CE et al. A change in human faecal flora in response to inclusion of gum arabic in the diet. Br.J.Nutr. 1986;55:261-6.