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CBD Synergies SP References

  1. Costello RB, et al. The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature. Nutr J. 2014; 13: 106.
  2. Esposito S, et al. Pediatric sleep disturbances and treatment with melatonin. J Transl Med. 2019; 17: 77.
  3. Vaughn LK, et al. Endocannabinoid signalling: has it got rhythm? Br J Pharmacol. 2010; 160(3): 530-543.
  4. Takata Y, et al. Sleep and wakefulness are controlled by ventral medial midbrain/pons GABAergic neurons in mice. J Neurosci. 2018; 38(47): 10080-10092.
  5. Yu X, et al. GABA and glutamate neurons in the VTA regulate sleep and wakefulness. Nature Neurosci. 2019; 22: 106-119.
  6. Plante DE, et al. The role of GABA in primary insomnia. Sleep. 2012; 35(6): 741-742.
  7. Yamatsu A, et al. Effect of oral γ-aminobutyric acid (GABA) administration on sleep and its absorption in humans. Food Sci Biotechnol. 2016; 25(2): 547-551.
  8. De Petrocellis L, Di Marzo V. An introduction to the endocannabinoid system: from the early to the latest concepts. Best Pract Res Clin Endocrinol Metab. 2009; 23(1): 1-15.
  9. Pava MJ, et al. Endocannabinoid signaling regulates sleep stability. PLoS One. 2016; 11(3): e0152473.
  10. Murillo-Rodriguez E, et al. The endocannabinoid system may modulate sleep disorders in aging. Curr Neuropharmacol. 2019; [ePub ahead of print].
  11. Pava ML, et al. Endocannabinoid modulation of cortical up-states and NREM sleep. PLoS One. 2014; 9(2): e88672.
  12. Kuhathasan N, et al. The use of cannabinoids for sleep: A critical review of clinical trials. Exp Clin Psychopharmacol. 2019; 27(4): 383-401.
  13. Linares IMP, et al. No acute effects of cannabidiol on the sleep-wake cycle of healthy subjects: A randomized, double-blind, placebo-controlled, crossover study. Front Pharmacol. 2018; 9: 315.
  14. Oikonomou G, et al. The serotonergic raphe promote sleep in zebrafish and mice. Neuron. 2019; 103(4): 686-701.
  15. Birdsall TC. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev. 1998; 3(4): 271-280.
  16. Gant C. The role of 5 HTP as a precursor for serotonin and melatonin in the treatment of anxiety, panic disorder, sleep disorder, weight management, fibromyalgia, migraine and withdrawal from antidepressant medication. 2004; Semantic Scholar. https://www.semanticscholar.org/paper/The-Role-of-5-HTP-as-a-Precursor-for-Serotonin-and-Gant/13b8bb6db36e7453c83355f35a069713af84d4ba.
  17. Zhao T, et al. Scutellaria baicalensis Georgi. (Lamiaceae): a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology. J Pharm Pharmacol. 2019; 71(9): 1353-1369.
  18. Shia Y, et al. Herbal insomnia medications that target GABAergic systems: A review of the psychopharmacological evidence. Curr Neuropharmacol. 2014; 12(3): 289-302.
  19. Elsas SM, et al. Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method. Phytomedicine. 2010; 17(12): 940-949.
  20. Guerrero FA, Medina GM. Effect of a medicinal plant (Passiflora incarnata L) on sleep. Sleep Sci. 2017; 10(3): 96-100.
  21. Toda K, et al. Passionflower extract induces high-amplitude rhythms without phase shifts in the expression of several circadian clock genes in vitro and in vivo. Int J Biomed Sci. 2017; 13(2): 84-92.
  22. Brown E, et al. Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. AANA J. 2007; 75(5): 333-337.
  23. Blessing EM, et al. Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics. 2015; 12(4): 825-836.
  24. Chagas MH, et al. Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson’s disease patients: a case series. J Clin Pharm Ther. 2014; 39(5): 564-566.
  25. Babson KA, et al. Cannabis, cannabinoids, and sleep: A review of the literature. Curr Psychiatry Rep. 2017; 19:23.
  26. Carlini EA, Cunha JM. Hypnotic and antiepileptic effects of cannabidiol. J Clin Pharmacol. 1981; 21(S1): 417S-427S.
  27. Wyatt RJ, et al. Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalogr Clin Neurophysiol. 1971; 30(6): 505-509.
  28. Zhao F, et al. Rumen-protected 5-hydroxytryptophan improves sheep melatonin synthesis in the pineal gland and intestinal tract. Med Sci Monit. 2019; 25: 3605-3616.
  29. Bendz LM, Scates AC. Melatonin treatment for insomnia in pediatric patients with attention-deficit/hyperactivity disorder. Ann Pharmacother. 2010; 44(1): 185-191.
  30. Alghamdi BS. The neuroprotective role of melatonin in neurological disorders. J Neurosci Res. 2018; 96(7): 1136-1149.
  31. Ferracioli-Oda E, et al. Meta-analysis: Melatonin for the treatment of primary sleep disorders. PLoS One. 2013; [online].
  32. Suhner A, et al. Comparative study to determine the optimal melatonin dosage form for the alleviation of jet lag. Chronobiol Int. 1998; 15(6): 655-666.
  33. Cicek SS. Structure-dependent activity of natural GABA(A) receptor modulators. Molecules. 2018; 23(7): 1512.
  34. Chang HH, et al. Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. J Ethnopharmacol. 2011; 135(2): 359-368.
  35. Hui KM, et al. Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochem Pharmacol. 2002; 64(9): 1415-1424.
  36. Elsas SM, et al. Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method. Phytomedicine. 2010; 17(12): 940-949.
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