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Melatonin Professional Dose References

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  4. Tahkamo L, et al. Systematic review of light exposure impact on human circadian rhythm. Chronobiol Int. 2019; 36(2): 151-170.
  5. Carlson LA, et al. Influence of exercise time of day on salivary melatonin responses. Int J Sports Physiol Perform. 2019; 14(3): 351-353.
  6. Xie Z, et al. A review of sleep disorders and melatonin. Neurol Res. 2017; 39(6): 559-565.
  7. Wurtman RJ. Age-related decreases in melatonin secretion—clinical consequences. J Clin Endocrinol Metab. 2000; 85(6): 2135-2136.
  8. Reiter RJ. Oxidative damage in the central nervous system: Protection by melatonin. Prog Neurobiol. 1998; 56(3): 359-384.
  9. Samantaray S, et al. Therapeutic potential of melatonin in traumatic central nervous system injury. J Pineal Res. 2009; 47(2): 134-142.
  10. Alghamdi BS. The neuroprotective role of melatonin in neurological disorders. J Neurosci Res. 2018; 96(7): 1136-1149.
  11. Lee JG, et al. The neuroprotective effects of melatonin: Possible role in the pathophysiology of neuropsychiatric disease. Brain Sci. 2019; 9(10): [online].
  12. Lewy AJ, et al. The circadian basis of winter depression. PNAS. 2006; 103(19): 7414-7419.
  13. Zisapel N. New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation. Br J Pharmacol. 2018; 175(16): 3190-3199.
  14. Benveniste A, et al. The glymphatic system and waste clearance with brain aging: A review. Gerontol. 2019; 65: 106-119.
  15. Siah KTH, et al. Melatonin for the treatment of irritable bowel syndrome. World J Gastroenterol. 2014; 20(10): 2492-2498.
  16. Zhu D, et al. Effects of melatonin on intestinal microbiota and oxidative stress in colitis mice. Biomed Res Int. 2018: 2607679.
  17. Xu P, et al. Melatonin prevents obesity through modulation of gut microbiota in mice. Pineal Res. 2017; 62(4): e12399.
  18. Sun H, et al. Effects of melatonin on cardiovascular diseases: progress in the past year. Curr Opin Lipidol. 2016; 27(4): 408-413.
  19. Ma S, et al. Melatonin ameliorates the progression of atherosclerosis via mitophagy activation and NLRP3 inflammasome inhibition. Oxid Med Cell Longev. 2018; 2018: 9286458.
  20. Owino S, et al. Melatonin signaling a key regulator of glucose homeostasis and energy metabolism. Front Endocrinol. 2019; 10: 488.
  21. Lima FB, et al. Pinealectomy causes glucose intolerance and decreases adipose cell responsiveness to insulin in rats. Am J Physiol. 1998; 275(6): E934-E941.
  22. Nogueira TC, et al. Absence of melatonin induces night-time hepatic insulin resistance and increased gluconeogenesis due to stimulation of nocturnal unfolded protein response. Endocrinol. 2011; 152(4): 1253-1263.
  23. Lo CC, et al. Effects of melatonin on glucose homeostasis, antioxidant ability, and adipokine secretion in ICR mice with NA/STZ-induced hyperglycemia. Nutrients. 2017; 9(11): 1187.
  24. Spiegel K, et al. Sleep loss: A novel risk factor for insulin resistance and type 2 diabetes. J Appl Physiol. 1985; 99(5): 2008-2019.
  25. Li Y, et al. Melatonin for the prevention and treatment of cancer. Oncotarget. 2017; 8(24): 39896-39921.
  26. Carrillo-Vico A, et al. Melatonin: Buffering the immune system. Int J Mol Sci. 14(4): 8638-8683.
  27. Haim A, Zubidat AE. Artificial light at night: melatonin as a mediator between the environment and epigenome. Philos Trans R Soc Lond B Biol Sci. 2015; 370(1667): 20140121.
  28. Zetner D, et al. Pharmacokinetics of alternative administration routes of melatonin: A systematic review. Drug Res (Stuttg). 2016; 66(4): 169-173.
  29. Zhang Q, et al. Construction of nanoscale liposomes loaded with melatonin via supercritical fluid technology. J Microencapsul. 2017; 34(7): 687-698.
  30. Ahn H, Park JH. Liposomal delivery systems for intestinal lymphatic drug transport. Biomater Res. 2016; 20: 36.
  31. Alyautdin R, et al. Nanoscale drug delivery systems and the blood-brain barrier. Int J Nanomedicine. 2014; 9: 795-811.
  32. Spector AA, et al. Membrane lipid composition and cellular function. J Lipid Res. 1985; 26(9): 1015-1035.
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