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NAD+ Platinum References

  1. Longo VD et al. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell 14 (4): 497-510. 
  2. Fang EF et al. NAD (+) in aging: molecular mechanisms and translational implications. Trends Mol Med. 2017;23(10):899–916
  3. Keller K and Engelhardt M. Strength and muscle mass loss with the aging process. Age and strength loss. Muscles Ligaments Tendons J. 2013; 3(4): 346-350.
  4. Chang AM and Halter JB. Aging and insulin secretion. Am J Physiol Endocrinol Metab. 2003; 284(1): E7-12.
  5. Caito SW and Aschner M. NAD+ Supplementation attenuates methylmercury dopaminergic and mitochondrial toxicity in Caenorhabditis Elegans. Toxicol Sci. 2016; 151(1): 139-149.
  6. Gizem Kivrak E, et al. Effects of electromagnetic fields exposure on the antioxidant defense system. J Microsc Ultrastruct. 2017; 2017; 5(4): 167-176.
  7. Xie N, et al. NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Signal Transduct Target Ther. 2020; 5: 227.
  8. Hong W, et al. Nicotinamide mononucleotide: A promising molecule for therapy of diverse diseases by targeting NAD+ metabolism. Front Cell Dev Biol. 2020.
  9. Wu, L et al. The elusive NMN transporter is found. Nat Metab 2019: 1; 8-9
  10. Yamaguchi S and Yoshino J. Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy. Bioessays. 2017; 39(5): 10.1002/bies.201600227.
  11. Guarente L, Franklin H. Epstein lecture: sirtuins, aging, and medicine. N Engl J Med. (2011) 364:2235–44.
  12. Kane AE, Sinclair DA. Sirtuins and NAD+ in the development and Treatment of Metabolic and Cardiovascular Diseases. Circ Res. 2018; 123:868-885.
  13. Mangerich A, et al. Pleiotropic cellular functions of PARP1 in longevity and aging: Genome maintenance meets inflammation. Oxid Med Cell Longev. 2012; 2012: 321653.
  14. Bonkowski MS and Sinclair D. Slowing aging by design: the rise of NAD+ and sirtuin-activating compounds. Nat Rev Mol Cell Biol. 2016; 17(11): 679-690.
  15. Lewinska A, et al. AMPK-mediated senolytic and senostatic activity of quercetin surface functionalized Fe3O4 nanoparticles during oxidant-induced senescence in human fibroblasts. Redox Biol. 2020; 28: 101337.
  16. Jesko H, et al. Sirtuins and their roles in brain aging and neurodegenerative disorders. Neurochem Res. 2017; 42(3): 876-890.
  17. Warren JL, et al. Regulation of adaptive immune cells by sirtuins. Front Endocrinol (Lausanne). 2019; 10:466.
  18. Radak Z, et al. The systemic role of SIRT1 in exercise mediated adaptation. Redox Biol. 2020; 35: 101467.
  19. Vargas-Ortiz K, et al. Exercise and sirtuins: A way to mitochondrial health in skeletal muscle. Int J Mol Sci. 2019; 20(11): 2717.
  20. Asher G, et al. SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell. 2008; 134(2): 317-328.
  21. Grabowska W, et al. Sirtuins, a promising target in slowing down the ageing process. Biogerontology. 2017; 18(4): 447-476.
  22. Schafer MJ, et al. Exercise prevents diet-induced cellular senescence in adipose tissue. Diabetes. 2016; 65(6): 1606-1615.
  23. Han YM, et al. β-Hydroxybutyrate prevents vascular senescence through hnRNP A1-mediated upregulation of Oct4. Mol Cell. 2018; 71(6): 1064-1078.
  24. Weng Z, et al. Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. PLoS One. 2012; 7(3): e33805.
  25. Mohar DS and Malik S. The sirtuin system: The holy grail of resveratrol? J Clin Exp Cardiol. 2012; 3(11): 216.
  26. Hustad S, et al. Riboflavin and methylenetetrahydrofolate reductase. Madame Curie Bioscience Database. 2013.
  27. Ahn H, Park JH. Liposomal delivery systems for intestinal lymphatic drug transport.Biomater Res. 2016 Nov 23;20:36View Full Paper
  28. Alyautdin R et al. Nanoscale drug delivery systems and the blood brain barrier.  Int J Nanomedicine. 2014 Feb 7;9:795-811View Full Paper
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