Quicksilver Scientific

Due to inclement weather and increased order volume expect shipping delays. 

Free shipping over $50


Unsupported Browser

This website will offer limited functionality in this browser. We only support the recent versions of major browsers like Chrome, Firefox, Safari, and Edge.

Vitamin C with R-Lipoc Acid References

  1. Bendich A et al. The antioxidant role of vitamin C. Adv Free Radic Biol Med. 1986;2:419-44 View Abstract
  2. Carr AC. Vitamin C and immune function. Nutrients. 2017 Nov 3;9(11). View Full Paper
  3. Stoyanovsky DA et al. Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid. Curr Eye Res. 1995 Mar;14(3):181-9. View Abstract
  4. Biewenga GP et al. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol. 1997 Sep;29(3):315-31. View Abstract
  5. Tibullo D et al. Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential. Inflamm Res. 2017 Nov;66(11):947-959. View Abstract
  6. Smith AR et al. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr Med Chem. 2004 May;11(9):1135-46. View Abstract
  7. Kagan VE et al. Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells. Biochim Biophys Acta. 2003 Mar 17;1620(1-3):72-84 View Abstract
  8. Kilic F et al. Modeling cortical cataractogenesis XX. In vitro effect of alpha-lipoic acid on glutathione concentrations in lens in model diabetic cataractogenesis. Biochem Mol Biol Int. 1998 Oct;46(3):585-95 View Abstract
  9. Hagen TM et al. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J. 1999 Feb;13(2):411-8. View Abstract
  10. Kramer K et al. R-alpha-lipoic acid. In: Kramer K, Hoppe P, Packer L, eds. Nutraceuticals in Health and Disease Prevention. New York: Marcel Dekker, Inc.; 2001:129-164.
  11. Schleicher RL et al. Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003–2004 National Health and Nutrition Examination Survey (NHANES). Am. J. Clin. Nutr. 2009, 90, 1252–1263. View Abstract
  12. Niki E. Interaction of ascorbate and alpha-tocopheral. Ann N Y Acad Sci. 1987;498:186-99. View Abstract
  13. McCay PB. Vitamin E: Interactions with free radicals and ascorbate. Ann. Rev. Nutr.1985 5:323-340 View Abstract
  14. Dormandy TL. Free-radical oxidation and antioxidants. Lancet 1978 i: 647-650 View Abstract
  15. Salehi B. Insights on the use of α-Lipoic acid for therapeutic purposes. Biomolecules. 2019 Aug 9;9(8). View Full Paper
  16. VE Kagan et al.Dihydrolipoic acid—a universal antioxidant both in the membrane and in the aqueous phase. Biochem Pharmacol, 44 (1992), pp. 1637-1649 View Abstract
  17. Shay KP et al. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 2009;1790:1149–1160. View Full Paper
  18. Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid. J Clin Biochem Nutr. 2015 Jul; 57(1): 21–26 View Abstract
  19. Goralska M et al. Alpha lipoic acid changes iron uptake and storage in lens epithelial cells. Exp. Eye Res. 2003, 76, 241–248. View Abstract
  20. Sun H et al. Alphalipoic Acid Prevents Oxidative Stress and Peripheral Neuropathy in Nab-Paclitaxel-Treated Rats through the Nrf2 Signalling Pathway. Oxid Med Cell Longev. 2019 Feb 10;2019:3142732. View Full Paper
  21. Geesin JC, Darr D et al. Ascorbic acid specifically increases type I and type III procollagen messenger RNA levels in human skin fibroblast. J Invest Dermatol 1988;90:420-424. View Abstract
  22. Ross R et al. Wound healing and collagen formation. II. Fine structure in experimental scurvy. J Cell Biol 1962;12:533-551.  View Abstract
  23. Kramer GM et al. Ascorbic acid treatment on early collagen production and wound healing in the guinea pig. J Periodontol 1979;50:189-192.  View Abstract
  24. DePhillipo NN et al. Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Orthop J Sports Med. 2018;6(10):2325967118804544. View Full Paper
  25. Geesin JC et al. Ascorbic acid specifically increases type I and type III procollagen messenger RNA levels in human skin fibroblast. J Invest Dermatol 1988;90:420-424. View Abstract
  26. Humbert PG, Haftek M et al. Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo. Exp Dermatol 2003;12:237-244. View Abstract
  27. Tebbe B, Wu S, et al. L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-1alpha and IL-6 in cultured human keratinocytes in vitro. J Invest Dermatol 1997;108:302-306 View Abstract
  28. Carr AC et al. Vitamin C and immune function. Nutrients. 2017;9(11):1211. Published 2017 Nov 3. View Full Paper
  29. Ran L et al. Extra dose of vitamin C based on a daily supplementation shortens the common cold: a meta-analysis of 9 randomized controlled trials. Biomed Res Int. 2018 Jul 5;2018:1837634. View Abstract
  30. Dinicola S et al. Alpha-Lipoic Acid downregulates IL-1 and IL-6 by DNA hypermethylation in SK-N-BE neuroblastoma cells. Antioxidant 2017, 6, 74. View Abstract
  31. Khalili M et al. Does lipoic acid consumption a_ect the cytokine profile in multiple sclerosis patients: A double-blind, placebo-controlled, randomized clinical trial. Neuroimmunomodulation 2014, 21, 291–296. View Abstract
  32. Zhang J et al. Regeneration of glutathione by α-lipoic acid via Nrf2/ARE signaling pathway alleviates cadmium-induced HepG2 cell toxicity.
  33. Environ Toxicol Pharmacol. 2017 Apr;51:30-37. View Abstract
  34. Shi C. α-Lipoic acid protects against the cytotoxicity and oxidative stress induced by cadmium in HepG2 cells through regeneration of glutathione by glutathione reductase via Nrf2/ARE signaling pathway.Environ Toxicol Pharmacol. 2016 Jul;45:274-81. View Abstract
  35. Harada S et al. An association between idiopathic Parkinson’s disease and polymorphisms of phase II detoxification enzymes: glutathione S-transferase M1 and quinone oxidoreductase 1 and 2. Biochem Biophys Res Commun. 2001 Nov 9;288(4):887-92 View Abstract
  36. Zhang Y. Phase II Enzymes. Encyclopedia of Cancer, Ed: Manfred Schwab. Springer 2011 View Full Paper
  37. Spector AA et al. Membrane lipid composition and cellular function. J Lipid Res. 1985 Sep;26(9):1015-35 View Full Paper
  38. Porter CJ. Drug delivery to the lymphatic system. Crit Rev Ther Drug Carrier Syst. 1997;14(4):333-93 View Full Paper
  39. Ahn H et al. Liposomal delivery systems for intestinal lymphatic drug transport. Biomater Res. 2016 Nov 23;20:36 View Full Paper
  40. Alyautdin R et al. Nanoscale drug delivery systems and the blood brain barrier. Int J Nanomedicine. 2014 Feb 7;9:795-811 View Full Paper
Your Cart