CBD Synergies - AX+ References
- Pacher P, Kunos G. Modulating the endocannabinoid system in human health and disease – successes and failures. FEBS Journal. 2013; 280(9): 1918-1943. doi: https://doi.org/10.1111/febs.12260
- McPartland JM, Guy GW, Di Marzo V. Care and feeding of the endocannabinoid system: A systematic review of potential clinical interventions that upregulate the endocannabinoid system. Romanovsky AA, ed. PLoS ONE. 2014; 9(3): e89566. doi: https://doi.org/10.1371/journal.pone.0089566
- Di Marzo V, Maccarrone M. FAAH, and anandamide: is 2-AG really the odd one out? Trends Pharmacol Sci. 2008; 29(5): 229-233. doi: https://doi.org/10.1016/j.tips.2008.03.001
- Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature. 1990; 346(6284): 561-564. doi: https://doi.org/10.1038/346561a0
- Munro S, Thomas KL, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature. 1993; 365(6441): 61-65. doi: https://doi.org/10.1038/365061a0
- Devane W, Hanus L, Breuer A, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science. 1992; 258(5090): 1946-1949. doi: https://doi.org/10.1126/science.1470919
- Morales P, Hurst DP, Reggio PH. Molecular targets of the phytocannabinoids: A complex picture. Prog Chem Org Nat Prod. 2017; 103: 103-131. doi: https://doi.org/10.1007/978-3-319-45541-9_4
- Citti C, Ciccarella G, Braghiroli D, Parenti C, Vandelli MA, Cannazza G. Medicinal cannabis: Principal cannabinoids concentration and their stability evaluated by a high-performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method. J Pharm Biomed Anal. 2016; 128: 201-209. doi: https://doi.org/10.1016/j.jpba.2016.05.033
- Turner SE, Williams CM, Iversen L, Whalley BJ. Molecular pharmacology of phytocannabinoids. Prog Chem Org Nat Prod. 2017; 103: 61-101. doi: https://doi.org/10.1007/978-3-319-45541-9_3
- Ligresti A, De Petrocellis L, Di Marzo V. From phytocannabinoids to cannabinoid receptors and endocannabinoids: Pleiotropic physiological and pathological roles through complex pharmacology. Physiol Rev. 2016; 96(4): 1593-1659. doi: https://doi.org/10.1152/physrev.00002.2016
- Mechoulam R, HanušL. Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects. Chem Phys Lipids. 2002; 121(1): 35-43. doi: https://doi.org/10.1016/S0009-3084(02)00144-5
- El-Alfy AT, Ivey K, Robinson K, et al. Antidepressant-like effect of Δ9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. Pharmacol Biochem Behav. 2010; 95(4): 434-442. doi: https://doi.org/10.1016/j.pbb.2010.03.004
- Ashton CH, Moore PB. Endocannabinoid system dysfunction in mood and related disorders. Acta Psychiatrica Scandinavica. 2011; 124(4): 250-261. doi: https://doi.org/10.1111/j.1600-0447.2011.01687.x
- Korem N, Zer-Aviv TM, Ganon-Elazar E, Abush H, Akirav I. Targeting the endocannabinoid system to treat anxiety-related disorders. J Basic Clin Physiol Pharmacol. 2016; 27(3). doi: https://doi.org/10.1515/jbcpp-2015-0058
- Blessing EM, Steenkamp MM, Manzanares J, Marmar CR. Cannabidiol is a potential treatment for anxiety disorders. Neurotherapeutics. 2015; 12(4): 825-836. doi:https://doi.org/10.1007/s13311-015-0387-1
- Mandolini GM, Lazzaretti M, Pigoni A, Oldani L, Delvecchio G, Brambilla P. Pharmacological properties of cannabidiol in the treatment of psychiatric disorders: a critical overview. Epidemiol Psychiatr Sci. 2018; 27(4): 327-335. doi: https://doi.org/10.1017/s2045796018000239
- Soares VP, Campos AC. Evidences for the anti-panic actions of cannabidiol. Curr Neuropharmacol. 2017; 15(2): 291-299. doi: https://doi.org/10.2174/1570159X14666160509123955
- Crippa JAS, Derenusson GN, Ferrari TB, et al. Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol (Oxford, England). 2011; 25(1): 121-130. doi: https://doi.org/10.1177/0269881110379283
- Linares IMP, Guimaraes FS, Eckeli A, et al. No acute effects of cannabidiol on the sleep-wake cycle of healthy subjects: A randomized, double-blind, placebo-controlled, crossover study. Front Pharmacol. 2018 ;9. doi: https://doi.org/10.3389/fphar.2018.00315
- Calapai F, Cardia L, Esposito E, et al. Pharmacological aspects and biological effects of cannabigerol and its synthetic derivatives. Evid Based Complement Alternat Med: eCAM. 2022; 2022: 3336516. doi: https://doi.org/10.1155/2022/3336516
- Russo EB, Cuttler C, Cooper ZD, Stueber A, Whiteley VL, Sexton M. Survey of patients employing cannabigerol predominant Cannabis preparations: Perceived medical effects, adverse events, and withdrawal symptoms. Cannabis Cannabinoid Res. 2021; 7(5). doi: https://doi.org/10.1089/can.2021.0058
- Bluett RJ, Joyonna Gamble-George, Hermanson DJ, Hartley ND, Marnett LJ, Patel S. Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. Transl Psychiatry. 2014; 4(7): e408-e408. doi: https://doi.org/10.1038/tp.2014.53
- Mock ED, Berend Gagestein, Mario. Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities. Prog Lipid Res. 2023; 89: 101194-101194. doi: https://doi.org/10.1016/j.plipres.2022.101194
- Baldwin D, Rudge S. The role of serotonin in depression and anxiety. Int Clin Psychopharmacol. 1995; 9: 41-46. doi: https://doi.org/10.1097/00004850-199501004-00006
- Birdsall TC. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev. 1998; 3(4): 271-280. https://pubmed.ncbi.nlm.nih.gov/9727088/
- Möhler H. The GABA system in anxiety and depression and its therapeutic potential. Neuropharmacology. 2012; 62(1): 42-53. doi: https://doi.org/10.1016/j.neuropharm.2011.08.040
- Lydiard RB. The role of GABA in anxiety disorders. J Clin Psychiatr. 2003; 64 Suppl 3: 21-27. https://pubmed.ncbi.nlm.nih.gov/12662130/
- Abdou AM, Higashiguchi S, Horie K, Kim M, Hatta H, Yokogoshi H. Relaxation and immunity enhancement effects of γ-Aminobutyric acid (GABA) administration in humans. BioFactors. 2006; 26(3): 201-208. doi: https://doi.org/10.1002/biof.5520260305
- Yoto A, Murao S, Motoki M, et al. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks. Amino Acids. 2012; 43(3): 1331-1337. doi: https://doi.org/10.1007/s00726-011-1206-6
- Mazzoli R, Pessione E. The neuro-endocrinological role of microbial glutamate and GABA signaling. Front Microbiol. 2016; 7. doi: https://doi.org/10.3389/fmicb.2016.01934
- Haskell CF, Kennedy DO, Milne AL, Wesnes KA, Scholey AB. The effects of l-theanine, caffeine, and their combination on cognition and mood. Biol Psychol. 2008; 77(2): 113-122. doi: https://doi.org/10.1016/j.biopsycho.2007.09.008
- Kimura K, Ozeki M, Juneja LR, Ohira H. l-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007; 74(1): 39-45. doi: https://doi.org/10.1016/j.biopsycho.2006.06.006
- Nathan PJ, Lu K, Gray M, Oliver C. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother. 2006; 6(2): 21-30. https://pubmed.ncbi.nlm.nih.gov/17182482/
- Shi Y, Dong JW, Zhao JH, Tang LN, Zhang JJ. Herbal insomnia medications that target GABAergic systems: A review of the psychopharmacological evidence. Curr Neuropharmacol. 2014; 12(3): 289-302. doi: https://doi.org/10.2174/1570159X11666131227001243
- Hui KM, Huen MSY, Wang HY, et al. The anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochem Pharmacol. 2002; 64(9): 1415-1424. doi: https://doi.org/10.1016/s0006-2952(02)01347-3
- Koulivand PH, Khaleghi Ghadiri M, Gorji A. Lavender and the Nervous System. Evid Based Complement Alternat Med. 2013; 2013 (681304):1-10. doi: https://doi.org/10.1155/2013/681304
- Yogi W, Tsukada M, Sato Y, et al. Influences of lavender essential oil inhalation on stress responses during short-duration sleep cycles: A pilot study. Healthcare. 2021; 9(7): 909. doi: https://doi.org/10.3390/healthcare9070909
