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Vitamin C + Elderberry References

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  2. De Clercq E, Li G. Approved antiviral drugs over the past 50 years. Clin Microbiol Rev. 2016; 29(3): 695-747.
  3. Sanjuan R and Domingo-Calap P. Mechanisms of viral mutation. Cell Mol Life Sci. 2016; 73(23): 4433-4448.
  4. Rikin S, et al. Assessment of temporally-related acute respiratory illness following influenza vaccination. Vaccine. 2018; 36(15): 1958-1964.
  5. Carr AC and Maggini S. Vitamin C and immune function. Nutrients. 2017; 9(11).
  6. Washko PW, et al. Ascorbic acid recycling in human neutrophils. J Biol Chem. 1993; 268(21): 15531-15535.
  7. Reshi ML, et al. RNA viruses: ROS-mediated cell death. Int J Cell Biol. 2014; 2014: 467452.
  8. Ware HH, et al. Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against bacterial infections. PLoS One. 2019; 14(2): e0208216.
  9. Lin X, et al. The influenza virus H5N1 infection can induce ROS production for viral replication and host cell death in A549 cells modulated by human Cu/Zn superoxide dismutase (SOD1) overexpression. Viruses. 2016; 8(1): 13.
  10. Pehlivan FE. Vitamin C: An antioxidant agent. Intech Open. 2017; DOI: 10.5772/intechopen.69660.
  11. Lenton KJ, et al. Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency. Am J Clin Nutr. 2003; 77(1): 189-195.
  12. Diotallevi M, et al. Glutathione fine-tunes the innate immune response toward antiviral pathways in a macrophage cell line independently of its antioxidant properties. Front Immunol. 2017; 8: 1239.
  13. Atherton JG, et al. The effect of ascorbic acid on infection of chick-embryo ciliated tracheal organ cultures by coronavirus. Arch Virol. 1978; 56: 195-199.
  14. Davelaar FG and Bos J. Ascorbic acid and infectious bronchitis infections in broilers. Avian Pathol. 1992; 21(4): 581-589.
  15. Hemila H and Douglas RM. Vitamin C and acute respiratory infections. Int J Tuberc Lung Dis. 1999; 3(9): 756-761.
  16. Silva da Costa L, et al. RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux. Cell Death & Dis. 2019; 10: 346.
  17. Tisoncik JR, et al. Into the eye of the cytokine storm. Microbiol Mol Biol Rev. 2012; 76(1): 16-32.
  18. Sang X, et al. Vitamin C inhibits the activation of the NLRP3 inflammasome by scavenging mitochondrial ROS. Inflammasome. 2016; 2(1): [online].
  19. Davis JL, et al. Liposomal-encapsulated ascorbic acid: Influence on vitamin C bioavailability and capacity to protect against ischemia-reperfusion injury. Nutr Metab Insights. 2016; 9: 25-30.
  20. Kim Y, et al. Vitamin C is an essential factor on the anti-viral immune responses through the production of interferon-α/β at the initial stage of Influenza A virus (H3N2) infection. Immune Netw. 2013; 13(2): 70-74.
  21. Mousavi S, et al. Immunomodulatory and antimicrobial effects of vitamin C. Eur J Microbiol Immunol (Bp). 2019; 9(3): 73-79.
  22. Torabian G, et al. Anti-influenza activity of elderberry (Sambucus nigra). J Funct Foods. 2019; 54: 353-360.
  23. Ho GTT, et al. Elderberry and elderflower extracts, phenolic compounds, and metabolites and their effect on complement, RAW 264.7 macrophages and dendritic cells. Int J Mol Sci. 2017; 18(3): [online].
  24. Simonyi A, et al. Inhibition of microglial activation by elderberry extracts and its phenolic components. Life Sci. 2015; 128: 30-38.
  25. Lavefve L, et al. Berry polyphenols metabolism and impact on human gut microbiota and health. Food & Funct. 2020: [online].
  26. Hawkins J, et al. Black elderberry (Sambucus Nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complement Ther Med. 2019; 42: 361-365.
  27. Tiralongo E, et al. Elderberry supplementation reduces cold duration and symptoms in air-travelers: a randomized, double-blind placebo-controlled clinical trial. 2016; 8(182): [online].
  28. Khomich OA, et al. Redox biology of respiratory viral infections. Viruses. 2018; 10(8): 392.
  29. Strugala P, et al. A comprehensive study on the biological activity of elderberry extract and cyanidin 3-O-glucoside and their interactions with membranes and human serum albumin. Molecules. 2018; 23(10): 2566.
  30. Serbinova E, et al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic Biol Med. 1991; 10(5): 263-275.
  31. Ren Z, et al. Dietary supplementation with tocotrienols enhances immune function in C57BL/6 mice. J Nutr. 2010; 140(7): 1335-1341.
  32. Lee GY and Han SN. The role of vitamin E in immunity. Nutrients. 2018; 10(11): 1614.
  33. Pour PM, et al. The signaling pathways, and therapeutic targets of antiviral agents: Focusing on the antiviral approaches and clinical perspectives of anthocyanins in the management of viral diseases. Front Pharmacol. 2019; 10: 1207.
  34. Arroyo-Maya IJ, et al. Biopolymer nanoparticles as potential delivery systems for anthocyanins: Fabrication and properties. Food Res Int. 2015; 69: 1-8.
  35. Chen BH, et al. Nanoemulsion and nanoliposome based strategies for improving anthocyanin stability and bioavailability. Nutrients. 2019; 11(5): 1052.
  36. Bryla A, et al. Encapsulation of elderberry extract into phospholipid nanoparticles. J Food Engineer. 2015; 167(B): 189-195.
  37. Ahn H, Park JH. Liposomal delivery systems for intestinal lymphatic drug transport. Biomater Res. 2016; 20: 36.
  38. Alyautdin R, et al. Nanoscale drug delivery systems and the blood-brain barrier. Int J Nanomedicine. 2014; 9: 795-811.
  39. Spector AA, et al. Membrane lipid composition and cellular function. J Lipid Res. 1985; 26(9): 1015-1035.
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