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IV Therapy and Liposomal Supplements: A Powerful Pair for Wellness

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Caitlin Holmes, MS, CNS

Clinical Nutritionist & Science Writer

IV Therapy and Liposomal Supplements: A Powerful Pair for Wellness

IV nutritional and antioxidant therapy has surged in popularity, embraced by athletes, busy professionals, celebrities, and wellness enthusiasts alike. From supporting energy and immunity to helping with recovery, IV therapy clinics offer targeted blends of nutrients like B vitamins, vitamin C, glutathione, and NAD+. These infusions are designed to deliver nutrients directly into your bloodstream for rapid uptake.

But what if you want to keep those benefits going between sessions, or prefer a more convenient option at home? That’s where liposomal supplements come into play. What’s more, IV therapy and liposomal supplements can work together to support your health goals.

What is IV Therapy?

IV (intravenous) nutritional therapy has become a popular way to deliver higher therapeutic dosages of vitamins, minerals, hydration, and other essential nutrients directly into your bloodstream for more efficient absorption. The advantage is that IV therapy bypasses the digestive tract, which normally slows or limits the absorption of nutrients. While certain IV therapies have been used in hospital settings for decades (e.g., saline drips), the use of IV therapies for supporting optimal health and wellness is a relatively new trend.

A growing number of trendy independent health clinics, spas, and even pop-up IV therapy “bars” offer “on-demand” IV nutritional therapy to individuals who are interested in taking a proactive approach with their health. Most clinics offer an extensive menu of options to suit the needs and goals of each customer.

Why Are More People Turning to IV Therapy?

Vitamins and minerals are essential for health. They are used in the processes that help you recover from workouts and common ailments, and help maintain energy and resilience. When these nutrients are not sufficiently consumed via the diet, or the body can’t maintain normal levels, individuals may become deficient in certain vitamins and minerals. Some health conditions may increase “nutrient wasting,” raising the body’s need for additional supplementation. Additionally, if the body is faced with chronic stress, nutrients can be used up more rapidly.

Because IV therapy delivers quick doses of nutrients, many are turning to it to promote optimal health and sufficient levels of vitamins and minerals.

Popular IV Therapies: B Vitamins, Vitamin C, Glutathione, and NAD+

B Vitamins: Essential for energy production and stress hormone regulation. Because of this, IV B vitamins are often chosen during times of fatigue or high stress.

Vitamin C: A favorite for immune support and antioxidant protection. Many people choose high-dose vitamin C infusions to help strengthen their defenses.

Glutathione: A major antioxidant in the body, glutathione supports detoxification, healthy inflammatory responses, and immune defenses. IV glutathione can quickly raise blood levels and may even support mood. More evidence is needed to understand the direct effect of IV glutathione on immune function.

NAD+ (nicotinamide adenine dinucleotide): Popular among longevity seekers and athletes, NAD+ infusions aim to optimize energy production and recovery.

IV Therapy Benefits and Considerations

One of the main reasons people are drawn to IV therapy is its enhanced nutrient bioavailability. By delivering fluids and nutrients directly into the bloodstream, IV therapy bypasses the digestive system, which usually limits how much of these substances can be absorbed. This method also allows nutrients to reach your cells quickly, often within minutes, compared to the hours it takes to digest and absorb them from food or traditionally delivered supplements, offering faster results. In a sense, IV therapy is like using a fast-pass lane at an amusement park; it bypasses the long line so you can get on the ride faster.

However, there are a few things to keep in mind with IV therapy. IV therapy requires both time and financial investment. A single infusion can take 30-60 minutes, and costs can range from $100 to $1000 depending on the treatment. While generally considered safe, it’s important to receive IV therapy from a reputable clinic with trained medical professionals who can assess your health history, review any medical contraindications, and ensure safety. For example, for people with kidney problems, IV nutrient therapies could cause magnesium or potassium imbalance or fluid overload. Additionally, there are some documented cases of damage to the liver and allergic reactions from IV therapy. This is why it is important to seek out clinics that take precautions to ensure your safety.

In general, more research is needed to fully understand the benefits of IV therapy outside of medical settings. Still, its growing popularity reflects the enthusiasm people have for proactive, innovative approaches to wellness.

Although IV therapy offers a novel way to approach wellness, many people would prefer a more convenient way to support nutrient repletion. Accessibility to a clinic could be an issue for many, as well as the high price tag, time commitment, and use of needles. In these cases, high-quality liposomal supplements are a welcome alternative. And if IV therapy is your preference, oral liposomal supplements can be used in between clinic visits to help maintain nutrient levels from the convenience of your home.

A Promising Adjunct: Liposomal Delivery of Nutrients

Liposomal supplements are dietary supplements where the active ingredients are encapsulated within small spherical structures called liposomes. Liposomes are microscopic, bi-layered lipid bubbles made from the same fats (e.g., phospholipids) as our cell membranes. When nutrients are encapsulated in liposomes, this protective layer shields them from degradation in the digestive system, helping more of the nutrients reach your bloodstream – not unlike IV therapy.

There's also impressive research on the benefits of several liposomal nutrients. For example, liposomal glutathione can support healthy immune function, and if you receive an IV glutathione infusion, supplementing with liposomal glutathione post IV, can help maintain healthy glutathione levels over the long term. Similarly, liposomal vitamin C offers a simple way to keep your immune system supported between vitamin C drips.

No IV clinic near you? Not a fan of needles? Not to worry. Regular supplementation with high absorption liposomal supplements like glutathione and vitamin C can help support and maintain healthy nutrient levels from home.

Beyond glutathione and vitamin C, other common IV therapy nutrients available in supplemental liposome delivery include B vitamins and NAD+ precursors like NMN. Whether you’re working to maintain healthy nutrient levels between IV visits or looking for a high absorption alternative to IV’s, liposomal B’s and liposomal NMN offer powerful support for energy production and stress resilience, healthy aging, and recovery. 

Choosing Quality Liposomal Supplements

Not all products labeled “liposomal” are created equal. Some brands may cut corners on quality. Look for brands that use in-house manufacturing, precision chemistry, and rigorous quality testing to ensure stability and absorption. Without these steps, you may not be getting the full benefit of the liposomal delivery system.

The Bottom Line on IV Therapy

IV therapy is an exciting tool for rapid nutrient replenishment and wellness support. Pairing these infusions with high-quality liposomal supplements can help you sustain those benefits in daily life, supporting your energy, immunity, and recovery without needles or extra clinic visits.

While generally safe under medical supervision, it is wise to consult with a licensed medical professional to determine if IV therapy is right for you.

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