A Constant Health Threat: Toxin Accumulation & High Toxic Burden

Toxin accumulation is a real threat to human health in the 21st century. Our world has become a toxic soup of chemical contaminants that are difficult to avoid. To combat this continual onslaught, it’s critical to support the body’s natural antioxidant and detoxification systems to help reduce toxic burden.

In a healthy state, our bodies are designed to process and remove toxic substances on an ongoing basis. However, in our high-tech, industrialized world, where intake of toxins exceeds the body’s excretion capabilities, toxins begin to accumulate within tissues and cells leading to a high toxic burden. A high toxic burden can impede the body’s natural antioxidant and detoxification systems, creating downstream barriers to toxin removal and leading to many symptoms and health decline.

  • 7 Signs of a High Toxic Burden

    1. Excessive fatigue
    2. Poor sleep
    3. GI symptoms such as bloat and gas
    4. Food and skin sensitivities
    5. Hyper-sensitive to smells such as perfumes, candles, and cleaning products
    6. Brain fog and concentration issues
    7. Mood swings and irritability
  • Common Toxins and Sources

    EXOGENOUS TOXINS - Environmental + external
    • Metals
    • Molds
    • Plasticizers
    • Medications

    ENDOGENOUS TOXINS - Produced by the body
    • Endotoxin [parts of bacteria]
    • Hormones
    • Metabolic byproducts [like carbon dioxide and ammonia]

Understanding the Body’s Detoxification Processes


The process of detoxification consists of three phases. In a healthy state, toxins are processed and removed from the cells and organs using enzymes and transporter proteins, leaving the body primarily through the kidneys, liver, and GI tract, although the lungs and skin are also important detoxification organs.

Phase I – Activate

Phase I takes place mostly in the liver however it can also occur in the brain, intestines, lungs, and kidneys. In this phase, lipid-soluble toxins are activated by special enzymes like CYP450 and then temporarily transformed into intermediate substances making them more reactive.

Phase II – Conjugate

Phase II takes this intermediate, reactive toxin and conjugates or links it to a molecule like glutathione via enzymatic reactions. This phase makes the toxin water-soluble and safe for transport out of the cell and through the body. 

Phase III – Filtrate and Excretion

Healthy bile flow supports the movement of conjugated toxins through the liver and kidneys for excretion. This phase helps prevent recirculation of toxins.

Quicksilver’s Push-Catch Model of Detoxification

Improperly designed detox protocols can result in recirculation of toxins throughout the body. The ‘push catch’ model of detoxification was developed by Quicksilver Scientific® and Dr. Shade to work with the body’s natural detoxification system and encompasses all three phases of detoxification which include: activation, conjugation, filtration and binding of toxins in the GI tract. This is the foundation of all our specially curated detoxification protocols.

“PUSH” (Phase I & II): We use potent nutrients and bitter phytonutrients to help activate critical biochemical pathways like Nrf2 to ‘push’ toxins from the cell to the blood, liver and kidneys.*

“CATCH” (Phase III): Bitter compounds support healthy bile flow to move toxins through the liver and kidneys for excretion. Binding agents like charcoal and bentonite clay intercept or ‘catch’ toxins in the intestines for removal, minimizing recirculation.*

Discover Quicksilver Scientific’s PushCatch® Detox Systems for Detoxification

Industry leading toxin removal protocols addressing all three phases of detoxification to safely mobilize, filter, and excrete contaminants.


Detoxification Level

Target Applications

What's Included

PushCatch® Liver Detox

PushCatch® Liver Detox

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With just 2 products and 2 steps, PushCatch® is a simple, yet effective program that may be tailored to your health goals.

Duration: 4 weeks. Purchase 1 protocol for 1 dose daily. Purchase 2 protocols for 2 doses daily.

PushCatch® Liver Detox is our best-selling cellular detoxification program designed to support all three phases of detoxification using science-backed ingredients. 

  • 1x Dr. Shade’s Liver Sauce®
  • 1x Ultra Binder® Stick Packs

PreTox System | Gentle Toxin Drainage + Clearing

PreTox System | Gentle Toxin Drainage + Clearing

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The Pretox System is a gentle drainage and clearing protocol that is designed to one of our formal detoxification protocols like Advanced PushCatch® or Qube® 2.0, or as a standalone, gentle detox.Duration: 4 weeks

Drainage and clearing of circulating toxins without mobilizing toxins from cells and tissues. Helps remove built-up stagnation and opens detoxification pathways.

  • 2x Dr. Shade's Bitter X
  • 2x Liposomal Vitamin C
  • 2x Kidney Care
  • 2x Membrane Mend®
  • 2x Ultra Binder® Sensitive

Advanced PushCatch® Detox System

Advanced PushCatch® Detox System

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An easy to follow 5 product protocol. 4-week moderate dosing protocol for a generalized detox and reset. 5 days on, 2 days off or 10 days on, 4 days off. Duration: 4 weeks

Mobilization of stored cellular toxins, filtration of toxins through bile flow and drainage. Additional antioxidant, immune modulation, and membrane support to clear multiple toxins.

  • 2x Dr. Shade's Liver Sauce®
  • 2x Ultra Binder® Stick Packs
  • 2x Kidney Care
  • 2x Membrane Mend®
  • 2x Liposomal Glutathione

Qube® 2.0 Professional Detoxification System

Qube® 2.0 Professional Detoxification System

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Qube® 2.0 is our most extensive and deepest detoxification program. This professional protocol must be done under the guidance of a certified practitioner.Duration: 4 weeks

Specific ingredients target the removal of metals like mercury and lead, molds, mycotoxins, plasticizers, and endocrine disruptors. The protocol also includes products to encourage a healthy inflammatory response and microbial support – both potential barriers to detox if unaddressed.

  • 3x Cat's Claw Elite
  • 4x Glutathione Complex
  • 2x NAD+ Platinum®
  • 5x Dr. Shade's LiverSauce®
  • 2x IMD 9 Grams
  • 3x EDTA With R-LipoicAcid.
  • 3x Ultra Binder® Sensitive
  • Formula
  • 2x CBD Synergies-PN
  • 4x Kidney Care