Quicksilver Delivery System
4 oz. (120 mL)
Artemisinin is an active constituent of the plant Artemisia annua, also known as sweet wormwood or Qinghaosu. Artemisinin is a sesquiterpene endoperoxide lactone, and the biological mechanism of action may partly be attributable to the generation of free radicals via heme-mediated or mitochondrial-activated degradation of endoperoxidase bridges.1,2 Sesquiterpene lactones are secondary metabolites of plants that play an important role in protecting plants from parasitic invaders, insects, and infection.3 They are bitter compounds, and as such may impact digestion in a manner similar to more commonly used digestive bitters such as gentian.*
Artemisinin and its derivatives have been widely studied for their effects against Plasmodium falciparum, the protozoan parasite which causes malaria, and are recommended by the World Health Organization in combination with other therapies as first-line treatment in endemic regions.4,5 Artemisinin may impact the flora of the digestive system, genitourinary tract, and beyond, being shown to have broad microbial balancing actions.*6,7 It also may impact biofilms which make infections such as Candida albicans resistant to treatment.*8
Because of the low bioavailability of traditional oral formulations of artemisinin, the use of derivatives such as artesunate (water-soluble) and artemether (oil-soluble) or alternate dosing strategies such as liposomes have been investigated. Liposomal delivery systems have been shown to lead to more stable artemisinin plasma concentrations,9 suggesting that they lead to an extended release and thereby prolonged systemic effect.* Additionally, more immediate effects have also been seen with liposomal formulations than conventional artemisinin.*
Quicksilver Delivery Systems ™ brings the power of intravenous therapy into a convenient oral delivery.* Our Quicksilver Delivery Systems™ improve upon liposomal and emulsification technology with smaller, more stable particles made from the highest-grade ingredients available. In addition to exceptional absorption rates, these very small liposomal and nanoemulsified particles enhance lymphatic circulation of nutrients and intracellular delivery.10,11 The phospholipids, inherent in the liposomal and nanoemulsified formats, nourish cell membranes, promoting proper function for the absorption of nutrients and the excretion of cellular waste products and toxins.*12
- 1.Meshnick SR. Int J Parasitol. 2002 Dec;32:1655-60.
- Sun C, et al. Microb Cell. 2015;2:14–25.
- Rodriguez E, et al. Phytochemistry. 1976 Jan;15:1573-80.
- White NJ. Science. 2008 Apr;320:330-4.
- WHO guidelines for the treatment of malaria. Geneva: World Health Organization, 2006.
- Bilia AR, et al. Evid Based Complement Alternat Med. 2014;2014:159819.
- Goswami S, et al. Antimicrob Agents Chemother. 2012;56:4594-607.
- De Cremer K, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):421-6.
- Isacchi B, et al. Eur J Pharm Biopharm. 2012 Apr;80:528-34.
- Ahn H, Park JH. Biomater Res. 2016 Nov 23;20:36.
- Alyautdin R, et al. Int J Nanomedicine. 2014 Feb 7;9:795-811
- Spector AA, Yorek MA. J Lipid Res. 1985 Sep;26(9):1015-35
Suggested Use: Take 1 teaspoon by mouth 1 to 3 times daily or as directed by your health professional. May be taken directly by mouth or mixed into water or juice (grapefruit juice is best). Take on empty stomach, at least 10 minutes before meals. Best taken in a cycle of 10 days on, and 4 days off. Store at room temperature. Do not take when pregnant or breastfeeding. It is advisable to monitor liver function enzymes during usage.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.